Phosphorus oxychloride → HCID 57468605, compound

HRID 1989094Notes

Reaction equation

HRID 1989094 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([C:12]2[CH:17]=[C:16]([C:18]([F:21])([F:20])[F:19])[NH:15][C:14](=O)[N:13]=2)[CH:5]=[CH:6][C:7]=1[C:8]([F:11])([F:10])[F:9].P(Cl)(Cl)([Cl:25])=O>>[Cl:25][C:14]1[N:13]=[C:12]([C:4]2[CH:5]=[CH:6][C:7]([C:8]([F:11])([F:10])[F:9])=[C:2]([F:1])[CH:3]=2)[CH:17]=[C:16]([C:18]([F:21])([F:20])[F:19])[N:15]=1

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 57468606HCID 57468606, compound

Product 1

HCID 57468605HCID 57468605, compound

Procedure

The title compound was prepared from 4-(3-fluoro-4-trifluoromethyl-phenyl)-6-trifluoromethyl-1H-pyrimidin-2-one (4.08 g, 12.5 mmol) and phosphoryl chloride (40 mL) according to the general procedure I. Obtained as a yellow solid (4.26 g, 99%). MS (EI) 344.0 [(M)+]; mp 41° C.

Sources & evidence

ORD record
ord-5c21418e04cb4cea8234e1d0314c98f6
Source dataset
uspto-grants-2010_01
Patent number
US07642264B2

Reaction notes

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