HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 2-Chloro-4-(3,4-dichlorophenyl)-6-trifluoromethylpyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 4-(3,4-dichloro-phenyl)-6-trifluoromethyl-1H-pyrimidin-2-one | HCID 57468607 | — |
| Product | 2-Chloro-4-(3,4-dichlorophenyl)-6-trifluoromethylpyrimidine | HCID 15477740 | — |
Reaction Steps
The title compound was prepared from 4-(3,4-dichloro-phenyl)-6-trifluoromethyl-1H-pyrimidin-2-one (5.72 g, 18.5 mmol) and phosphoryl chloride (60 mL) according to the general procedure I. Obtained as a white solid (6.04 g, 99%). MS (EI) 326.0 [(M)+]; mp 82° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07642264B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-dbc962a23bcb437d9cc3bf27a229853b |
| Source note | uspto-grants-2010_01 |