Phosphorus oxychloride → HCID 57468611, compound

HRID 1989097Notes

Reaction equation

HRID 1989097 reaction equation
[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([C:14]2[CH:19]=[C:18]([C:20]([F:23])([F:22])[F:21])[NH:17][C:16](=O)[N:15]=2)[CH:7]=[CH:8][C:9]=1[C:10]([F:13])([F:12])[F:11])[CH3:2].P(Cl)(Cl)([Cl:27])=O>>[Cl:27][C:16]1[N:15]=[C:14]([C:6]2[CH:7]=[CH:8][C:9]([C:10]([F:13])([F:12])[F:11])=[C:4]([O:3][CH2:1][CH3:2])[CH:5]=2)[CH:19]=[C:18]([C:20]([F:23])([F:22])[F:21])[N:17]=1

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 57468612HCID 57468612, compound

Product 1

HCID 57468611HCID 57468611, compound

Procedure

The title compound was prepared from 4-(3-ethoxy-4-trifluoromethyl-phenyl)-6-trifluoromethyl-1H-pyrimidin-2-one (3.74 g, 10.6 mmol) and phosphoryl chloride (35 mL) according to the general procedure I. Obtained as a light brown solid. MS (EI) 370.0 [(M)+]; mp 89° C.

Workup

  1. customObtained as a light brown solid

Sources & evidence

ORD record
ord-fcb40faede494d2bba45a517b8acc09b
Source dataset
uspto-grants-2010_01
Patent number
US07642264B2

Reaction notes

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