Phosphorus oxychloride → HCID 57468659, compound

HRID 1989118Notes

Reaction equation

HRID 1989118 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:14]=[C:13]([CH3:15])[NH:12][C:11](=O)[N:10]=2)[CH:5]=[CH:6][C:7]=1[Cl:8].O=P(Cl)(Cl)[Cl:19]>>[Cl:19][C:11]1[N:10]=[C:9]([C:4]2[CH:5]=[CH:6][C:7]([Cl:8])=[C:2]([Cl:1])[CH:3]=2)[CH:14]=[C:13]([CH3:15])[N:12]=1

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 574686604-(3,4-Dichloro-phenyl)-6-methyl-1h-pyrimidin-2-one

Product 1

HCID 57468659HCID 57468659, compound

Procedure

The title compound was prepared from 4-(3,4-dichloro-phenyl)-6-methyl-1H-pyrimidin-2-one (2.51 g, 9.84 mmol) and phosphoroxychloride (35 mL) according to the general procedure I. Obtained as a brown solid (1.55 g, 58%). MS (EI) 272.1 [(M)+]; mp 123° C. (dec.).

Sources & evidence

ORD record
ord-f9876bdaeb794818b5f93729c053a90f
Source dataset
uspto-grants-2010_01
Patent number
US07642264B2

Reaction notes

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