HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4-(4-chloro-phenyl)-6-methyl-pyridine → 4-(4-Chloro-phenyl)-2-(4-iodo-imidazol-1-yl)-6-methyl-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4-(4-chloro-phenyl)-6-methyl-pyridine | HCID 57468639 | — |
| Reactant | HCID 178506559 | HCID 178506559 | — |
| Product | 4-(4-Chloro-phenyl)-2-(4-iodo-imidazol-1-yl)-6-methyl-pyridine | HCID 57468749 | — |
Reaction Steps
The title compound was prepared 2-chloro-4-(4-chloro-phenyl)-6-methyl-pyridine (example A.27) (2.3 g, 10 mmol) and commercially available 4-iodo-imidazole (2.248 g, 12 mmol) according to the general procedure IVa. Obtained as an off-white solid (2.1 g, 55%). MS (ISP) 396.0 [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07642264B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-3d8b72ec0b2242ed8eb996545d4844c7 |
| Source note | uspto-grants-2010_01 |