HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4-(3,4-dichlorophenyl)-6-trifluoromethylpyrimidine → 4-(3,4-Dichloro-phenyl)-2-(4-iodo-imidazol-1-yl)-6-trifluoromethyl-pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4-(3,4-dichlorophenyl)-6-trifluoromethylpyrimidine | HCID 15477740 | — |
| Reactant | HCID 178506559 | HCID 178506559 | — |
| Product | 4-(3,4-Dichloro-phenyl)-2-(4-iodo-imidazol-1-yl)-6-trifluoromethyl-pyrimidine | HCID 57468788 | — |
Reaction Steps
The title compound was prepared from 2-chloro-4-(3,4-dichloro-phenyl)-6-trifluoromethyl-pyrimidine (example A.7) (1.97 g, 6.0 mmol) and commercially available 4-iodo-imidazole (1.28 g, 6.6 mmol) according to the general procedure IVa. Obtained as an off-white solid (2.67 g, 92%). MS (ISP) 485.1 [(M+H)+]; mp 223° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07642264B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-dac8bdd407dc4750ba0a79296ad433d5 |
| Source note | uspto-grants-2010_01 |