HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dibromopyridine → HCID 86615446, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dibromopyridine | HCID 12274 | — |
| Reactant | 2-Iodo-4-methyl-6-(4-trifluoromethyl-phenyl)pyridine | HCID 57468682 | — |
| Catalyst | HCID 178419263 | HCID 178419263 | — |
| Product | HCID 86615446 | HCID 86615446 | — |
Reaction Steps
The title compound was prepared from 2-iodo-4-methyl-6-(4-trifluoromethyl-phenyl)pyridine (example A.58) (5.81 g, 16 mmol), n-BuLi/ZnBr2 and commercially available 2,6-dibromopyridine (5.31 g, 22.4 mmol) according to Tetrahedron Letters 1996, 37(15), 2537 and the general procedure IVc protocol b. Obtained as a white solid (2.34 g, 37%). MS (ISP) 393.0 [(M+H)+] and 395.0 [(M+2+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07642264B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-c90eae2dce1940a9a00e65a3db443584 |
| Source note | uspto-grants-2010_01 |