HCID 57468683, compound → 2'-Chloro-4-(3-methoxy-4-trifluoromethylphenyl)-6-methyl-[2,4']bipyridinyl

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Reaction Steps

The title compound was prepared from trifluoro-methanesulfonic acid 4-(3-methoxy-4-trifluoromethyl-phenyl)-6-methyl-pyridin-2-yl ester (example A.59) (2.0 g, 5.0 mmol) and commercially available 2-chloropyridine boronic acid (0.758 g, 5.0 mmol) according to the general procedure IVb; Obtained as an off-white solid (1.50 g, 82%). MS (ISP) 379.2 [(M+H)+] and 381 [(M+2+H)+].

Provenance & Evidence