3-Cyanophenylboronic acid → HCID 57469007, compound

HRID 1989549Notes

Reaction equation

HRID 1989549 reaction equation
[CH3:1][C:2]1[N:7]=[C:6](OS(C(F)(F)F)(=O)=O)[CH:5]=[C:4]([C:16]2[CH:21]=[CH:20][C:19]([C:22]([F:25])([F:24])[F:23])=[CH:18][CH:17]=2)[CH:3]=1.[C:26]([C:28]1[CH:29]=[C:30](B(O)O)[CH:31]=[CH:32][CH:33]=1)#[N:27]>>[CH3:1][C:2]1[N:7]=[C:6]([C:32]2[CH:33]=[C:28]([CH:29]=[CH:30][CH:31]=2)[C:26]#[N:27])[CH:5]=[C:4]([C:16]2[CH:21]=[CH:20][C:19]([C:22]([F:25])([F:24])[F:23])=[CH:18][CH:17]=2)[CH:3]=1

Participants

3

Reactant 2

HCID 27343253-Cyanophenylboronic acidHCID 57468647Trifluoro-methanesulfonic acid 6-methyl-4-(4-trifluoromethyl-phenyl)-pyridin-2-yl ester

Product 1

HCID 57469007HCID 57469007, compound

Procedure

The title compound was prepared trifluoro-methanesulfonic acid 6-methyl-4-(4-trifluoromethyl-phenyl)-pyridin-2-yl ester (example A.32) (5.00 g, 13 mmol) and commercially available 3-cyanophenylboronic acid (1.67 g, 14.3 mmol) according to the general procedure VI. Obtained as a white solid (3.00 g, 68%). MS (ISP) 339.1 [(M+H)+]; mp 140° C.

Sources & evidence

ORD record
ord-afe7cc935d624641aa8c87a2d6bfcfb5
Source dataset
uspto-grants-2010_01
Patent number
US07642264B2

Reaction notes

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