2-Bromopyridine → HCID 63680969, compound

HRID 1989826Notes

Reaction equation

Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N:3]=1.[F:8][C:9]1[CH:14]=[CH:13][C:12](B(O)O)=[CH:11][C:10]=1[CH:18]=[O:19]>>[F:8][C:9]1[CH:14]=[CH:13][C:12]([C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][N:3]=2)=[CH:11][C:10]=1[CH:18]=[O:19]

Participants

Reactant 2

HCID 79732-Bromopyridine

HCID 2778651(4-Fluoro-3-formylphenyl)boronic acid

Product 1

HCID 63680969HCID 63680969, compoundYield 64%

Procedure

General Procedure G using 2-bromopyridin and 4-fluoro-3-formylbenzeneboronic acid gave the title compound as colourless crystals in 64% yield.

Sources & evidence

ORD record: ord-c8090b6bf45d4edda28702e8b250bbbb
Source dataset: uspto-grants-2010_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07642367B2

Reaction notes

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