HCID 12518666, compound → HCID 86615571, compound

HRID 1989848Notes

Reaction equation

HRID 1989848 reaction equation
[CH3:1][O:2][C:3]1[CH:20]=[CH:19][C:18]2[C:17]3[CH2:16][CH2:15][C:14]4[C:9](=[CH:10][CH:11]=[C:12]([O:21][CH3:22])[CH:13]=4)[C:8]=3[CH2:7][CH2:6][C:5]=2[CH:4]=1>[Pd]>[CH3:22][O:21][C:12]1[CH:11]=[CH:10][C:9]2[C:8]3[C:17](=[C:18]4[C:5](=[CH:6][CH:7]=3)[CH:4]=[C:3]([O:2][CH3:1])[CH:20]=[CH:19]4)[CH:16]=[CH:15][C:14]=2[CH:13]=1

Participants

3

Reactant 1

HCID 12518666HCID 12518666, compound

Product 1

HCID 86615571HCID 86615571, compoundYield 35%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Conditions

Temperature
200 °C

Procedure

Under an argon gas flow, 70 g (0.24 mol) of 2,8-dimethoxy-5,6,11,12-tetrahydrochrysene and 50 g of Pd/C were charged into a 5 L round bottom flask equipped with a condenser, and heated at 200° C. for 1 h. Thereafter, the obtained reaction mixture was heated to 300° C. and sublimated. The resultant reaction product was recrystallized with acetic acid, thereby obtaining 24 g of the aimed product (yield: 35%).

Workup

  1. customequipped with a condenser
  2. customThereafter, the obtained reaction mixture
  3. temperaturewas heated to 300° C.
  4. customThe resultant reaction product
  5. customwas recrystallized with acetic acid

Sources & evidence

ORD record
ord-50f86266483442d69c3944858a801fa3
Source dataset
uspto-grants-2010_01
Patent number
US07642380B2

Reaction notes

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