HCID 68524247, compound → HCID 68526305, compound

HRID 1989850Notes

Reaction equation

HRID 1989850 reaction equation
[C:1](=[C:4]1[CH2:9][CH2:8][C:7]([CH2:11][OH:12])([CH3:10])[CH:6]=[CH:5]1)([CH3:3])[CH3:2]>[Pd].C(O)(C)C>[CH:1]([C:4]1[CH2:9][CH2:8][C:7]([CH2:11][OH:12])([CH3:10])[CH2:6][CH:5]=1)([CH3:3])[CH3:2]

Participants

4

Reactant 1

HCID 68524247HCID 68524247, compound

Product 1

HCID 68526305HCID 68526305, compoundYield 73%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 3776IsopropanolSolvent

Procedure

A glass reaction vessel was charged with 10 g of 4-isopropylidene-1-methyl-2-cyclohexenylmethanol produced by the same method as used in Example 1, 0.05 g of 5% Pd/C (water content: 53%) and 20 mL of isopropanol, and the contents of the reaction vessel were reacted with each other at a pressure of from 0.1 to 0.4 MPa and a temperature of 30° C. for 4.5 h. Thereafter, at the time at which the amount of hydrogen consumed reached 1.2 moles per 1 mole of the raw material, the reaction was stopped, and the reaction mixture was filtered to remove the catalyst therefrom, and then concentrated to obtain 4-isopropyl-1-methyl-3-cyclohexenylmethanol with a yield of 73%.

Workup

  1. customA glass reaction vessel
  2. customproduced by the same method
  3. customthe contents of the reaction vessel were reacted with each other at a pressure of from 0.1 to 0.4 MPa
  4. customThereafter, at the time at which the amount of hydrogen consumed
  5. filtrationthe reaction mixture was filtered
  6. customto remove the catalyst
  7. concentrationconcentrated

Sources & evidence

ORD record
ord-36bc65ca290c47a2a75148c8e3ed1c10
Source dataset
uspto-grants-2010_01
Patent number
US07642385B2

Reaction notes

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