HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → HCID 68522053, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | HCID 68522041 | HCID 68522041 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 68522053 | HCID 68522053 | 95% |
Reaction Steps
Add 3 mL of 2N dimethylamine in THF to 3-(4-iodophenyl)-4-cyano-5-methanesulfonyl-thiophene-2-carboxylic acid ethyl ester (0.23 mmol) and stir under nitrogen at room temperature for 2 h. Evaporate to dryness to provide the title compound which is used without further purification. Yield 95%. MS (ES+, m/e)=427 (M++1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07642361B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-3bf257af067040969837c0bf03c2d292 |
| Source note | uspto-grants-2010_01 |