HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → HCID 58873203, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | HCID 58873081 | HCID 58873081 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 58873203 | HCID 58873203 | — |
Reaction Steps
Add 4-cyano-3-(2′-cyano-biphenyl-4-yl)-5-methanesulfonyl-thiophene-2-carboxylic acid ethyl ester (100 mg, 0.23 mmol) to 3 mL of 2N dimethylamine in THF and stir under nitrogen at room temperature for 90 minutes. Evaporate to a tan solid which is used without further purification. MS(ES+, m/e)=402 (M++1); HPLC=89%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07642361B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-8bc41672fc23463ab3183565ad4486b2 |
| Source note | uspto-grants-2010_01 |