Hydrochloric Acid → HCID 16046205, compound

Participants

Reaction Steps

Add NaOH 1M (1 ml) to a suspension of 3-(4-tert-butyl-phenyl)-4-cyano-5-methylsulfanyl-thiophene-2-carboxylic acid ethyl ester (general preparation 28, general preparation 29, general example E-1) (0.128 mmol) in ethanol (1 ml) and stir 24 h. Add 6 N HCl until pH approx. 1 and white solid precipitates. Filter the solid to provide the title compound: MS (ES+, m/e): 332 (M+1).

Provenance & Evidence