HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1,3,3-Tetramethylguanidine → HCID 67397587, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1,3,3-Tetramethylguanidine | HCID 66460 | — |
| Reactant | 2,4-Oxazolidinedione | HCID 97389 | — |
| Reactant | HCID 13340133 | HCID 13340133 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 67397587 | HCID 67397587 | — |
Reaction Steps
A solution of 3 g (11.90 mmol) of 1-(4-bromobutyl)-1H-indole, prepared in stage 2.1., of 2.41 g (23.80 mmol) of 1,3-oxazolidin-2,4-dione (J. Med. Chem., 1991, 34, 1538-1544) and of 2.74 g (23.80 mmol) of 1,1,3,3-tetramethylguanidine in 30 ml of tetrahydrofuran is brought to reflux for 14 hours under an inert atmosphere.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07645757B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-f10e43c407044bfcb8a90169a70605d9 |
| Source note | uspto-grants-2010_01 |