Glyoxylic Acid → HCID 10822776, compound

HRID 1990775Notes

Reaction equation

HRID 1990775 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10](=[O:12])[CH3:11])=[CH:5][CH:4]=1.[C:13]([OH:17])(=[O:16])[CH:14]=O>>[OH:12][C:10]1([CH3:11])[O:17][C:13](=[O:16])[CH:14]=[C:9]1[C:6]1[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=1

Participants

3

Reactant 2

HCID 760Glyoxylic AcidHCID 312311-(p-Methoxyphenyl)-2-propanone

Product 1

HCID 10822776HCID 10822776, compound

Procedure

16.42 g (0.10 mol) of 4-methoxyphenylacetone and an aqueous solution of 45% glyoxylic acid (19.4 ml, 0.11 mol) were stirred overnight at 100° C. The reaction liquid was concentrated under reduced pressure to obtain a crude product of 5-hydroxy-4-(4-methoxyphenyl)-5-methyl-5H-furan-2-one.

Workup

  1. customThe reaction liquid
  2. concentrationwas concentrated under reduced pressure

Sources & evidence

ORD record
ord-bab1986a345a4bc3844caff7dc58b182
Source dataset
uspto-grants-2010_01
Patent number
US07645756B2

Reaction notes

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