HCID 86607634, compound → 4-Chloro-3-(2-fluoroethoxy)benzaldehyde

Participants

Reaction Steps

To a solution of [4-chloro-3-(2-fluoro-ethoxy)-phenyl]-methanol (1.19 g, 5.82 mmol, 1.0 equiv) in dichloromethane (60 mL) was added activated MnO2 (10.1 g, 116.31 mmol, 20.0 equiv). The reaction mixture was stirred vigorously for 6 h at ambient temperature and then filtered through Hyflo Super Cel providing after evaporation of the solvent under reduced pressure 0.91 g (77%) of the title compound. MS (EI): 202.0 [M]+.

Provenance & Evidence