HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminotetrahydropyran → HCID 24789143, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminotetrahydropyran | HCID 419223 | — |
| Reactant | Potassium hydroxy sulfite | HCID 23707502 | — |
| Reactant | HCID 59128646 | HCID 59128646 | — |
| Product | HCID 24789143 | HCID 24789143 | — |
Reaction Steps
6-[5-(1H-Imidazol-2-yl)-2-methyl-phenyl]-8-methyl-2-methylsulfanyl-8H-pyrido[2,3-d]pyrimidin-7-one was treated with OXONE™ following the procedure of step 3 of Example 1, and the resulting sulfonyl compound was treated with 4-amino-tetrahydropyran using the procedure of step 4 of Example 1, to give 2.5 mg of 6-[5-(1H-imidazol-2-yl)-2-methyl-phenyl]-8-methyl-2-(tetrahydro-pyran-4-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one: MS (M+H)=417.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07645764B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-1150397c839d47c19580b5ec9baeb7e7 |
| Source note | uspto-grants-2010_01 |