Hydrochloric Acid → HCID 68536288, compound

HRID 1991055Notes

Reaction equation

HRID 1991055 reaction equation
C[O:2][C:3](=[O:19])/[CH:4]=[CH:5]/[C:6]1[CH:15]=[CH:14][C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[C:7]=1[N+:16]([O-:18])=[O:17].[OH-].[Na+].O.Cl>CO>[N+:16]([C:7]1[C:8]2[C:13](=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:14]=[CH:15][C:6]=1/[CH:5]=[CH:4]/[C:3]([OH:19])=[O:2])([O-:18])=[O:17]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 962Water2×HCID 14798Sodium HydroxideHCID 68535324HCID 68535324, compound

Product 1

HCID 68536288HCID 68536288, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

(E)-3-(Nitronaphthalen-2-yl)-acrylic acid methyl ester (1.3 g, 5.05 mmol) was dissolved in MeOH (50 ml) and treated with 2N NaOH (3.8 ml; 7.6 mmol) and water (25 ml) for 1 hour at 50° C. The mixture was acidified with 2N HCl (4.2 ml; 8.33 mmol), water (100 ml) added and filtered to render the desired acid as yellow crystals (1.05 g; 80%).

Workup

  1. additionadded
  2. filtrationfiltered

Sources & evidence

ORD record
ord-3697f1ae1f904ee09c6988cbf7600f93
Source dataset
uspto-grants-2010_01
Patent number
US07645760B2

Reaction notes

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