Benzo(B)Thiophene-2-Boronic Acid → HCID 11167094, compound

HRID 1991373Notes

Reaction equation

HRID 1991373 reaction equation
Br[C:2]1[CH:3]=[C:4]([C:17]([OH:24])=[C:18]([C:20]([CH3:23])([CH3:22])[CH3:21])[CH:19]=1)[C:5]([NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]#[N:15])=[CH:10][C:9]=1[Cl:16])=[O:6].[S:25]1[C:29]2[CH:30]=[CH:31][CH:32]=[CH:33][C:28]=2[CH:27]=[C:26]1B(O)O>>[S:25]1[C:26]([C:2]2[CH:19]=[C:18]([C:20]([CH3:23])([CH3:22])[CH3:21])[C:17]([OH:24])=[C:4]([CH:3]=2)[C:5]([NH:7][C:8]2[CH:13]=[CH:12][C:11]([C:14]#[N:15])=[CH:10][C:9]=2[Cl:16])=[O:6])=[CH:27][C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][C:29]1=2

Participants

3

Reactant 2

HCID 2359Benzo(B)Thiophene-2-Boronic AcidHCID 60102088HCID 60102088, compound

Product 1

HCID 11167094HCID 11167094, compound

Procedure

The title compound was prepared from 3-bromo-5-tert-butyl-N-(2-chloro-4-cyanophenyl)-6-hydroxy-benzamide and benzothiophen-2-boronic acid

Sources & evidence

ORD record
ord-2259b2f8f7af451ca9be2e341d62fdc9
Source dataset
uspto-grants-2010_01
Patent number
US07645791B2

Reaction notes

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