HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylamine → HCID 137227822, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylamine | HCID 7912 | — |
| Reactant | (2R)-1-[(tert-butoxy)carbonyl]piperidine-2-carboxylic acid | HCID 688618 | — |
| Reactant | Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 9886157 | — |
| Reactant | HCID 178491258 | HCID 178491258 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 137227822 | HCID 137227822 | — |
Reaction Steps
23 mg (0.1 mmol) of Boc-D-Pipecolic Acid were treated with 0.1 mmol [Dimethylamino-([1,2,3]triazolo[4,5-b]pyridin-3-yloxy)-methylene]-dimethyl-ammonium hexafluorophosphate (HATU) and Diisopropylamine (DIPEA) in 1 ml Dimethylforamide (DMF) for 10 min. 17 mg (0.1 mmol) of N-Hydroxy-4-methoxy-benzamidine were added and the reaction stirred at room temperature for 20 min. The product was not further characterized.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07645776B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-a120ba423126409eb80bdc6d46562a2d |
| Source note | uspto-grants-2010_01 |