Trifluoroacetic acid → HCID 68687777, compound

HRID 1991399Notes

Reaction equation

C(OC([N:8]1[CH2:13][CH2:12][CH2:11][CH2:10][C@@H:9]1[C:14]1[O:18][N:17]=[C:16]([C:19]2[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[CH:21][CH:20]=2)[N:15]=1)=O)(C)(C)C.[F:27][C:28]([F:33])([F:32])[C:29]([OH:31])=[O:30]>>[F:27][C:28]([F:33])([F:32])[C:29]([OH:31])=[O:30].[CH3:26][O:25][C:22]1[CH:21]=[CH:20][C:19]([C:16]2[N:15]=[C:14]([C@H:9]3[CH2:10][CH2:11][CH2:12][CH2:13][NH:8]3)[O:18][N:17]=2)=[CH:24][CH:23]=1

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 68687079HCID 68687079, compound

Product 1

HCID 68687777HCID 68687777, compound

Procedure

Crude material from step 2 was treated with neat trifluoroacetic acid (TFA) at room temperature for 1 h. The TFA was evaporated. The crude product not further characterized.

Workup

customThe TFA was evaporated

Sources & evidence

ORD record: ord-0aac9ffec3974470bf8343c5776e079b
Source dataset: uspto-grants-2010_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07645776B2

Reaction notes

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