Hydrogen Bromide → Bupropion

HRID 1991915Notes

Reaction equation

[CH3:1][CH:2]([NH:12][C:13]([CH3:16])([CH3:15])[CH3:14])[C:3]([C:5]1[CH:6]=[CH:7][CH:8]=[C:9]([Cl:11])[CH:10]=1)=[O:4].Cl.Br>>[CH3:1][CH:2]([NH:12][C:13]([CH3:14])([CH3:16])[CH3:15])[C:3]([C:5]1[CH:6]=[CH:7][CH:8]=[C:9]([Cl:11])[CH:10]=1)=[O:4]

Participants

Reactant 2

HCID 260Hydrogen Bromide

HCID 62884Bupropion Hydrochloride

Product 1

HCID 444Bupropion

Procedure

Bupropion HCl was replaced with HBr and adjusted to obtain same amount Bupropion base.

Sources & evidence

ORD record: ord-5ef7bd527c08407ea74982eb728e7b31
Source dataset: uspto-grants-2010_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07645901B2

Reaction notes

Loading…