Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 23134841 | HCID 23134841 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 23134842 | HCID 23134842 | 95% |
Reaction Steps
About 10 g (about 27.148 mmol) of 4-[6-(3,4,5-Trifluoro-phenoxy)-hexyloxy]-benzoic acid was dissolved in about 200 ml of methylene chloride, and then added with about 3.55 g (about 29.862 mmol) of thionyl chloride. The reaction mixture was stirred at about 35° C. for about 6 hours, and the solvent was removed. Through a vacuum drying process, the desired compound was obtained (Yield about 95%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07646014B2 |
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| Source dataset | uspto-grants-2010_01 |
|---|
| ORD ID | ord-34bc26401e06496780bfefbbd42bd56e |
|---|
| Source note | uspto-grants-2010_01 |
|---|
