Sodium Persulfate → HCID 58728611, compound

HRID 1992220Notes

Reaction equation

HRID 1992220 reaction equation
[NH2:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([F:11])[C:3]=1[C:4]([OH:6])=[O:5].S(OOS([O-])(=O)=O)([O-])(=O)=[O:13].[Na+].[Na+]>[OH-].[Na+].O>[NH2:1][C:2]1[C:10]([OH:13])=[CH:9][CH:8]=[C:7]([F:11])[C:3]=1[C:4]([OH:6])=[O:5]

Participants

5

Reactant 2

HCID 62655Sodium PersulfateHCID 5211422-Amino-6-fluorobenzoic acid

Product 1

HCID 58728611HCID 58728611, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 14798Sodium HydroxideSolvent

Procedure

2-amino-6-fluorobenzoic acid (5.00 g, 32.2 mmole) was dissolved in 30 ml of 2N sodium hydroxide. To this was added dropwise a solution of sodium persulfate (7.67 g, 32.2 mmole) in 80 ml of water. After stirring over night the resulting black solution was extracted with 2 L of ether and 1 L of ethylacetate. Evaporation of the water gave a black solid that was used with no purification.

Workup

  1. extractionwas extracted with 2 L of ether and 1 L of ethylacetate
  2. customEvaporation of the water
  3. customgave a black solid that
  4. customwas used with no purification

Sources & evidence

ORD record
ord-77d702e545fc4dc2aead326567f18d31
Source dataset
uspto-grants-2010_01
Patent number
US07645771B2

Reaction notes

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