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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1992373Generated: October 30, 2026

Hydrochloric Acid → 2-(3,4-Difluorophenyl)acetaldehyde

https://huagongshe.com/reaction/1992373

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1,2-Difluoro-4-(2-methoxy-vinyl)-benzeneHCID 68521985—
SolventAcetoneHCID 180—
Product2-(3,4-Difluorophenyl)acetaldehydeHCID 22667325—

Reaction Conditions

Temperature45 °C

Reaction Steps

To a solution of 1,2-difluoro-4-(2-methoxy-vinyl)-benzene (5.5 g, 0.032 mol, from step (i) above) in 80 ml acetone was added 66 ml of 3 (M) HCl and stirred at 45° C. for 4 h. Acetone was evaporated under reduced pressure and the residue was

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07648985B2
Source datasetuspto-grants-2010_01
ORD IDord-03a39ec233bd4b9b9046549dcbae6da1
Source noteuspto-grants-2010_01