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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1992465Generated: October 25, 2026

1-(Benzenesulfonyl)piperazine → (4-Benzenesulfonyl-piperazin-1-yl)-[5-(4-isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-methanone

https://huagongshe.com/reaction/1992465

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Benzenesulfonyl)piperazineHCID 808712—
Reactant[5-(4-Isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-(4-methanesulfonyl-piperazin-1-yl)-methanoneHCID 68538245—
Product(4-Benzenesulfonyl-piperazin-1-yl)-[5-(4-isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-methanoneHCID 6853584692%

Reaction Steps

The title compound was synthesized in analogy to example 1, from 5-(4-isopropyl-piperazine-1-carbonyl)-1H-indole-2-carboxylic acid hydrochloride (example 1, intermediate b) and 1-benzenesulfonyl-piperazine to afford the desired product as a light-brown foam (92%). MS (ISP): 524.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07648979B2
Source datasetuspto-grants-2010_01
ORD IDord-8f7edb21f40146ef83d62e0a66e79c67
Source noteuspto-grants-2010_01