HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloropyridine-4-boronic acid → HCID 24986210, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloropyridine-4-boronic acid | HCID 5151595 | — |
| Reactant | {4-[5-(4-Isopropyl-piperazine-1-carbonyl)-1H-indole-2-carbonyl]-piperazin-1-yl}-piperidin-1-yl-methanone | HCID 68533742 | — |
| Product | HCID 24986210 | HCID 24986210 | 62% |
Reaction Steps
The title compound was synthesized in analogy to example 5, after stirring for 3.5 days at 35° C., from {4-[5-(4-isopropyl-piperazine-1-carbonyl)-1H-indole-2-carbonyl]-piperazin-1-yl}-piperidin-1-yl-methanone (example 14) and 2-chloropyridine-4-boronic acid to afford the desired product as a light-brown foam (62%). MS (ISP): 606.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07648979B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-4820eaf14d8b43b087b7f4daa3d37d5c |
| Source note | uspto-grants-2010_01 |