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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1992489Generated: October 30, 2026

1-Piperazinecarboxylic acid, ethyl ester → HCID 68535485, compound

https://huagongshe.com/reaction/1992489

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Piperazinecarboxylic acid, ethyl esterHCID 8431—
Reactant[5-(4-Isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-(4-methanesulfonyl-piperazin-1-yl)-methanoneHCID 68538245—
ProductHCID 68535485HCID 6853548572%

Reaction Steps

The title compound was synthesized in analogy to example 1, from 5-(4-isopropyl-piperazine-1-carbonyl)-1H-indole-2-carboxylic acid hydrochloride (example 1, intermediate b) and 1-ethoxycarbonylpiperazine to afford the desired product as a light-brown solid (72%). MS (ISP): 456.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07648979B2
Source datasetuspto-grants-2010_01
ORD IDord-a993a5cdb9f04a45ba084221c8a512bb
Source noteuspto-grants-2010_01