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HRID1992565

反应详情

EQUATION

反应方程式

HRID 1992565 的结构方程式

REACTANTS

反应物

2
结构：Br
HCID260

Hydrogen Bromide

BrH

2 次

结构：COc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12
HCID2585

Carvedilol

C24H26N2O4

PRODUCTS

生成物

1
结构：Br.COc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12
HCID9957094

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CC(=O)O
溶剂HCID176

Acetic Acid

C2H4O2

结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

Carvedilol free base is dissolved in ethanol, and anhydrous HBr is added (HBr in acetic acid). The solution is cooled, and crystallization ensues. The product is filtered, washed with process solvent, and dried.

WORKUP

后处理

  1. temperatureThe solution is cooled
  2. customcrystallization ensues
  3. filtrationThe product is filtered
  4. washwashed with process solvent
  5. customdried