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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 199258Generated: October 30, 2026

Hydrochloric Acid → 5-Bromo-2-[4-({[2'-fluoro-4'-(methylsulfonyl)-4-biphenylyl]oxy}methyl)-1-piperidinyl]pyrimidine

https://huagongshe.com/reaction/199258

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDimethyl SulfoxideHCID 679—
ReactantPotassium CationHCID 813—
ReactantMethanolHCID 887—
ReactantCarbonate IonHCID 19660—
Reactant5-Bromo-2-chloropyrimidineHCID 606665—
Reactant4-[[4-(2-Fluoro-4-methylsulfonylphenyl)phenoxy]methyl]piperidineHCID 66673429—
Product5-Bromo-2-[4-({[2'-fluoro-4'-(methylsulfonyl)-4-biphenylyl]oxy}methyl)-1-piperidinyl]pyrimidineHCID 24994030—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-e9d3a06ee5764b8687dfee75f69b1a62
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)