Hydrochloric Acid → 5-Bromo-2-[4-({[2'-fluoro-4'-(methylsulfonyl)-4-biphenylyl]oxy}methyl)-1-piperidinyl]pyrimidine
Reaction equation
[CH3:41][OH:42].[CH3:43][S:44]([CH3:45])=[O:46].[Cl:27][c:28]1[n:29][cH:30][c:31]([Br:34])[cH:32][n:33]1.[ClH:1].[F:2][c:3]1[c:4](-[c:13]2[cH:14][cH:15][c:16]([O:19][CH2:20][CH:21]3[CH2:22][CH2:23][NH:24][CH2:25][CH2:26]3)[cH:17][cH:18]2)[cH:5][cH:6][c:7]([S:9](=[O:10])(=[O:11])[CH3:12])[cH:8]1.[K+:35].[K+:36].[O-:37][C:38]([O-:39])=[O:40]>>[F:2][c:3]1[c:4](-[c:13]2[cH:14][cH:15][c:16]([O:19][CH2:20][CH:21]3[CH2:22][CH2:23][N:24]([c:28]4[n:29][cH:30][c:31]([Br:34])[cH:32][n:33]4)[CH2:25][CH2:26]3)[cH:17][cH:18]2)[cH:5][cH:6][c:7]([S:9](=[O:10])(=[O:11])[CH3:12])[cH:8]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-e9d3a06ee5764b8687dfee75f69b1a62
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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