HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,5-Dibromopyridine → 4-(5-bromopyridin-2-yl)benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,5-Dibromopyridine | HCID 69353 | — |
| Reactant | 4-Formylphenylboronic Acid | HCID 591073 | — |
| Product | 4-(5-bromopyridin-2-yl)benzaldehyde | HCID 11849714 | — |
Reaction Steps
Scheme 40, Example 1, illustrates the coupling reaction of 4-formylphenylboronic acid 40.1 with 2,5-dibromopyridine 40.11, using the procedure described above, to afford 4-(5-bromo-2-pyridyl)benzaldehyde 40.12. This compound is then coupled, as described above, with a dialkyl phosphite 40.4, to afford the pyridyl phosphonate 40.13.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07649015B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-3acdece82eed400ba6d8d48bbdcb1e71 |
| Source note | uspto-grants-2010_01 |