反应详情

A solution of CH3CN (30 mL) of crude 6 (2.5 g) was cooled to 0° C., and treated with TMSBr (8 g, 52 mmol) for 5 hr. The reaction mixture was stirred with methanol for 1.5 hr at room temperature, concentrated, recharged with methanol, concentrated to dryness to give crude 7 which was used for next reaction without further purification.

1. concentrationconcentrated
2. concentrationconcentrated to dryness
3. customto give crude 7 which
4. customwas used for next reaction without further purification