3-Methylbenzaldehyde → HCID 136102574, compound

HRID 1993405Notes

Reaction equation

HRID 1993405 reaction equation
[N:1]1([C:7]2[N:12]=[CH:11][NH:10][C:9](=[O:13])[CH:8]=2)[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[C:14]1([CH3:22])[CH:19]=[CH:18][CH:17]=[C:16]([CH:20]=O)[CH:15]=1>>[CH3:22][C:14]1[CH:15]=[C:16]([CH:17]=[CH:18][CH:19]=1)[CH2:20][N:4]1[CH2:5][CH2:6][N:1]([C:7]2[N:12]=[CH:11][NH:10][C:9](=[O:13])[CH:8]=2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 121053-MethylbenzaldehydeHCID 1361025406-piperazin-1-yl-3H-pyrimidin-4-one2×

Product 1

HCID 136102574HCID 136102574, compound

Procedure

6-[4-(3-Methyl-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one was prepared using Procedure A from 6-piperazin-1-yl-3H-pyrimidin-4-one (Intermediate 4) and m-tolualdehyde. Mass spectrum (ES) MH+=285.

Sources & evidence

ORD record
ord-0719b280ac274262982f68ef170fd2e6
Source dataset
uspto-grants-2010_01
Patent number
US07652013B2

Reaction notes

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