3-Nitrobenzaldehyde → HCID 136102570, compound

HRID 1993430Notes

Reaction equation

HRID 1993430 reaction equation
[N:1]1([C:7]2[N:12]=[CH:11][NH:10][C:9](=[O:13])[CH:8]=2)[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[N+:14]([C:17]1[CH:18]=[C:19]([CH:22]=[CH:23][CH:24]=1)[CH:20]=O)([O-:16])=[O:15]>>[N+:14]([C:17]1[CH:18]=[C:19]([CH:22]=[CH:23][CH:24]=1)[CH2:20][N:4]1[CH2:5][CH2:6][N:1]([C:7]2[N:12]=[CH:11][NH:10][C:9](=[O:13])[CH:8]=2)[CH2:2][CH2:3]1)([O-:16])=[O:15]

Participants

3

Reactant 2

HCID 74493-NitrobenzaldehydeHCID 1361025406-piperazin-1-yl-3H-pyrimidin-4-one2×

Product 1

HCID 136102570HCID 136102570, compound

Procedure

6-[4-(3-Nitro-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one was prepared using Procedure A from 6-piperazin-1-yl-3H-pyrimidin-4-one (Intermediate 4) and 3-nitrobenzaldehyde. Mass spectrum (ES) MH+=316.

Sources & evidence

ORD record
ord-dcae4d584a234d318e8d5860875b746e
Source dataset
uspto-grants-2010_01
Patent number
US07652013B2

Reaction notes

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