Salicylaldehyde → HCID 136102578, compound

HRID 1993434Notes

Reaction equation

HRID 1993434 reaction equation
[N:1]1([C:7]2[N:12]=[CH:11][NH:10][C:9](=[O:13])[CH:8]=2)[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[CH:14](=O)[C:15]1[C:16](=[CH:18][CH:19]=[CH:20][CH:21]=1)[OH:17]>>[OH:17][C:16]1[CH:18]=[CH:19][CH:20]=[CH:21][C:15]=1[CH2:14][N:4]1[CH2:5][CH2:6][N:1]([C:7]2[N:12]=[CH:11][NH:10][C:9](=[O:13])[CH:8]=2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 6998SalicylaldehydeHCID 1361025406-piperazin-1-yl-3H-pyrimidin-4-one2×

Product 1

HCID 136102578HCID 136102578, compound

Procedure

6-[4-(2-Hydroxy-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one was prepared using Procedure A from 6-piperazin-1-yl-3H-pyrimidin-4-one (Intermediate 4) and salicylaldehyde. Mass spectrum (ES) MH+=287.

Sources & evidence

ORD record
ord-02feb37ce856422e8bd711805d740a08
Source dataset
uspto-grants-2010_01
Patent number
US07652013B2

Reaction notes

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