HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(1,1'-Biphenyl)-2-carboxaldehyde → 6-(4-Biphenyl-2-ylmethyl-piperazin-1-yl)-3H-pyrimidin-4-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (1,1'-Biphenyl)-2-carboxaldehyde | HCID 121052 | — |
| Edukt | 6-piperazin-1-yl-3H-pyrimidin-4-one | HCID 136102540 | — |
| Produkt | 6-(4-Biphenyl-2-ylmethyl-piperazin-1-yl)-3H-pyrimidin-4-one | HCID 136102573 | — |
Reaktionsschritte
6-(4-Biphenyl-2-ylmethyl-piperazin-1-yl)-3H-pyrimidin-4-one was prepared using Procedure B from 6-piperazin-1-yl-3H-pyrimidin-4-one (Intermediate 4) and 2-phenylbenzaldehyde (available from Aldrich). 1H NMR (400 MHz, CDCl3) δ 2.36-2.39 (m, 4H), 3.43-3.48 (m, 6H), 5.32 (s, 1H), 7.25-7.40 (m, 8H), 7.80 (s, 1H), 12.20 (br s, 1H). Mass spectrum (ES) MH+=347.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07652013B2 |
| Quelldatensatz | uspto-grants-2010_01 |
| ORD ID | ord-7325a087abf6407cb0c4196372c054b7 |
| Quellennotiz | uspto-grants-2010_01 |