HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Iodosalicylaldehyde → HCID 136102562, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Iodosalicylaldehyde | HCID 252612 | — |
| Reactant | 6-piperazin-1-yl-3H-pyrimidin-4-one | HCID 136102540 | — |
| Product | HCID 136102562 | HCID 136102562 | — |
Reaction Steps
6-[4-(2-Hydroxy-5-iodo-benzyl)-piperazin-1-yl]-3H -pyrimidin-4-one was prepared using Procedure B from 6-piperazin-1-yl-3H-pyrimidin-4-one (Intermediate 4) and 5-iodosalicylaldehyde (available from Aldrich). 1H NMR (400 MHz, DMSO-d6) δ 2.42-2.47 (m, 4H), 3.28-3.55 (m, 6H), 5.26 (s, 1H), 6.61-6.63 (m, 1H), 7.38-7.46 (m, 2H), 7.84 (s, 1H), 10.30 (br s, 1H), 11.63 (br s, 1H). Mass spectrum (ES) MH+=413.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07652013B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-e7b314487bc240acba78862667008672 |
| Source note | uspto-grants-2010_01 |