HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Ethylphenyl isocyanate → 1-[4-(2-Chloro-pyridin-4-yloxy)-phenyl]-3-(4-ethyl-phenyl)-urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Ethylphenyl isocyanate | HCID 90007 | — |
| Reactant | 4-(2-Chloro-pyridin-4-yloxy)-phenylamine | HCID 57833430 | — |
| Product | 1-[4-(2-Chloro-pyridin-4-yloxy)-phenyl]-3-(4-ethyl-phenyl)-urea | HCID 58659406 | — |
Reaction Steps
The title compound is prepared as described in Example 102 but using 4-(2-chloro-pyridin-4-yloxy)-phenylamine (Example 105) and 4-ethyl-phenyl-isocyanate. The reaction mixture is stirred for 4 h. The title compound is obtained as a beige solid: ES-MS: 368.0 [M+H]+; single peak at tR=9.85 min (System 2); Rf=0.36 (CH2Cl2/Et2O, 90/10).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07652022B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-a22c5cf90f554462a52b4a3f7579c385 |
| Source note | uspto-grants-2010_01 |