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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1993549Erstellt: 26. Oktober 2026

4-Ethylphenyl isocyanate → 1-(4-Ethyl-phenyl)-3-[4-(6-trifluoromethyl-pyrimidin-4-yloxy)-phenyl]-urea

https://huagongshe.com/reaction/1993549

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt4-Ethylphenyl isocyanateHCID 90007—
Edukt1-p-Tolyl-3-[4-(6-trifluoromethyl-pyrimidin-4-yloxy)-phenyl]-ureaHCID 58659339—
Produkt1-(4-Ethyl-phenyl)-3-[4-(6-trifluoromethyl-pyrimidin-4-yloxy)-phenyl]-ureaHCID 58659328—

Reaktionsschritte

The title compound is prepared as described in Example 102 but using 4-(6-trifluoromethyl-pyrimidin-4-yloxy)-phenylamine (Example 114) and 4-ethyl-phenyl-isocyanate. The reaction mixture is stirred for 2.5 h. The title compound is obtained as a white solid: ES-MS: 403.0 [M+H]+; single peak at tR=9.72 min (System 2).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07652022B2
Quelldatensatzuspto-grants-2010_01
ORD IDord-eee240416961411d9ff20cdbf0dbebcf
Quellennotizuspto-grants-2010_01