HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylimidazole → 2-Methyl-1-(4-nitro-2-(trifluoromethyl)phenyl)-1H-imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylimidazole | HCID 12749 | — |
| Reactant | 2-Bromo-5-nitrobenzotrifluoride | HCID 136198 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | 2-Methyl-1-(4-nitro-2-(trifluoromethyl)phenyl)-1H-imidazole | HCID 59822451 | — |
Reaction Steps
The title compound is prepared by hearing 1-bromo-4-nitro-2-trifluoromethyl-benzene and 2-methyl-imidazole between 100-150° C. during 15 h: M+H=272.0; Rf (MeOH/CH2Cl2=1:5): 0.60.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07652022B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-4c402a8c4a9f4514871c7c8f08c57bb3 |
| Source note | uspto-grants-2010_01 |