HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutyryl chloride → N-[4-(5-Cyano-1-methyl-1H-pyrrol-2-yl)phenyl]-2-methylpropanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutyryl chloride | HCID 62325 | — |
| Reactant | 5-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrile | HCID 16050430 | — |
| Product | N-[4-(5-Cyano-1-methyl-1H-pyrrol-2-yl)phenyl]-2-methylpropanamide | HCID 16037461 | — |
Reaction Steps
The title compound was prepared according to the general procedure for acylation of 5-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrile using isobutyryl chloride (58 μL, 0.55 mmol) to provide N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]-2-methylpropanamide (0.026 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07652062B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-473f93b5f50e4a95a031891c0e4414aa |
| Source note | uspto-grants-2010_01 |