Methacryloyl chloride → HCID 16037549, compound

HRID 1993952Notes

Reaction equation

HRID 1993952 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]([CH3:13])[C:11]([C:14]#[N:15])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[CH3:16][C:17](=[CH2:21])[C:18](Cl)=[O:19]>>[C:14]([C:11]1[N:12]([CH3:13])[C:8]([C:5]2[CH:6]=[CH:7][C:2]([NH:1][C:18](=[O:19])[C:17]([CH3:21])=[CH2:16])=[CH:3][CH:4]=2)=[CH:9][CH:10]=1)#[N:15]

Participants

3

Reactant 2

HCID 13528Methacryloyl chlorideHCID 160504305-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrile

Product 1

HCID 16037549HCID 16037549, compound

Procedure

The title compound was prepared according to the general procedure for acylation of 5-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrile using 2-methyl-acryloyl chloride (53 μL, 0.55 mmol) to provide N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]-2-methylacrylamide (0.037 g).

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-b69704a1f4cb4e13b4094ae9edbe4a16
Source dataset
uspto-grants-2010_01
Patent number
US07652062B2

Reaction notes

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