反应详情

温度

130 °C

75.0 g of 1-bromoadamantane (349 mmol), 9.58 g of 1,3-dihydroxybenzene (87.0 mmol), 25 mL of toluene and stirrer were charged in a 300 mL recovery flask and heated and agitated at 130° C. for 24 hours under nitrogen flow. A solvent was removed under reduced pressure to obtain a solid. The obtained solid was purified by column chromatography, thus obtaining 23.0 g of 4,6-di(1-adamantyl)-1,3-dihydroxybenzene (60.8 mmol; the yield was 69.9%).

1. temperatureheated
2. customA solvent was removed under reduced pressure
3. customto obtain a solid
4. customThe obtained solid was purified by column chromatography