Potassium hydride → HCID 12799866, compound

Participants

Reaction Steps

The operation is as in Example 1, starting from 14 g of ethyl quinoline-2-carboxylate, 17.4 g of ethyl 3-[3-(N-benzoyl)piperidyl]propionate and 36 ml of a 20% suspension of potassium hydride in oil. 7.4 g of 1-(2-quinolyl)-3-(3-piperidyl)-1-propanone are obtained, which is converted into its monohydrochloride. This monohydrochloride is recrystallized from ethanol. Its melting point, after recrystallization from ethanol, is 198° C.

Provenance & Evidence