Potassium Hydroxide → HCID 12799867, compound

Participants

Reaction Steps

The operation is as in Example 13, but starting from 6 g of 1-(2-quinolyl)-3-(3-piperidyl)-1-propanone, 6 ml of 85% hydrazine hydrate and 5 g of potassium hydroxide pellets. 4.9 g of crude product are obtained. This product is absorbed on a column of 150 g of silica and eluted with a 9/1 chloroform-diethylamine mixture. 1.5 g of 2-[3-(3-piperidyl)-propyl]-quinoline are thus obtained, which melts at 194° C.

Provenance & Evidence