HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 13189017, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 3-(2-Chloroethyl)-3-azabicyclo[3.2.2]nonane--hydrogen chloride (1/1) | HCID 12612326 | — |
| Reactant | 1,2,3,4-Tetrahydro-5H-[1]benzopyrano[3,4-c]pyridin-5-one | HCID 13136922 | — |
| Product | HCID 13189017 | HCID 13189017 | 64.8% |
Reaction Steps
Prepared by the method described for Example 1 from 1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-c]pyridin-5-one (1.5 g, 0.007 moles), triethylamine (2.2 ml, 0.016 moles), and 3-(2-chloroethyl)-3-azabicyclo[3.2.2]nonane hydrochloride (1.7 g, 0.0076 moles). Recrystallization from ethanol gave the product (1.6 g) as the monohydrochloride, 5:1 hydrate, mp 267° C. (dec).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04404138 |
| Source dataset | uspto-grants-1983_09 |
| ORD ID | ord-31b1463bd945480b8f147a5e7424cabe |
| Source note | uspto-grants-1983_09 |