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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1995346Generated: October 30, 2026

Hydrazine hydrate (1:1) → HCID 20488255, compound

https://huagongshe.com/reaction/1995346

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrazine hydrate (1:1)HCID 24654—
ReactantEthyl 4,4,4-trifluorobut-2-enoateHCID 141226—
ReactantHCID 20488259HCID 20488259—
ProductHCID 20488255HCID 20488255—

Reaction Steps

In the same manner, reaction of α-phenyl-4-morpholinoacetonitrile with ethyl 3-trifluoromethylacrylate, followed by treatment of the resulting 3-trifluoromethyl-3-(benzoyl)propionic acid with hydrazine hydrate gives 6-phenyl-5-trifluoromethyl-4,5-dihydro-3(2H)-pyridazinone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04404203
Source datasetuspto-grants-1983_09
ORD IDord-b658522f995e483ca8b15a12f544b362
Source noteuspto-grants-1983_09